Newly diagnosed adults with Philadelphia chromosome-positive (Ph+) chronic myeloid leukaemia (CML) in chronic phase. Adults with chronic, accelerated, or myeloid or lymphoid blast phase Ph+ CML with resistance or intolerance to prior therapy including imatinib. Adults with Philadelphia chromosome-positive acute lymphoblastic leukaemia (Ph+ ALL) with resistance or intolerance to prior therapy. Paediatric patients 1 year of age and older with Ph+ CML in chronic phase. Paediatric patients 1 year of age and older with newly diagnosed Ph+ ALL in combination with chemotherapy.

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